Addison's disease is a disease that affects the hormonal or endocrine systems. Addison's disease transpires in all age group and in males and females similarly. Also denoted to as Primary Adrenal Insufficiency. The disease is said to be genetic in nature due to its occurrence in multiple family members, with further than one endocrine deficiency.
The reasons, in most cases, are the continuing destruction of the adrenal cortex or outer layer of the adrenal glands, by the immune system. 80% of the cases are triggered by autoimmune disorders The adrenal glands do not create enough cortical and in some cases
Addison's is caused by a botch by the body to produce tolerable levels of the hormone cortical. This can happen for a diversity of reasons. The problem may be due to a illness of the adrenal glands themselves; primary adrenal insufficiency or to insufficient excretion of ACTH by the pituitary gland; secondary adrenal insufficiency.
Analysis is frequently difficult, predominantly in the early stages. An analysis of a patient's medical history based on the signs, particularly the skin pigmentation changes will lead to a conclusion. The conclusion of the diagnosis is found by testing. The tests are intended at determining the adequacy of the levels of cortical and establishing the source. X-rays of the adrenal and pituitary glands are useful in founding the cause.